In detail, what is Psoriasis?
Psoriasis occurs when skin cells multiply too fast. Normally the skin renews itself every 3 or 4 weeks. In psoriasis sufferers it happens every 3 to 7 days. This overproduction breaks down the protective skin barrier, allowing the escape of moisture and the build-up of plaques of thick, scaling skin.
Symptoms include red and inflamed skin, often covered with loose, silver-coloured scales. The affected skin can be itchy and painful; sometimes it cracks and bleeds.
Psoriasis can really affect your quality of life. The visible symptoms can often make you self-conscious, and the constant itching can be annoying and exhausting. Many psoriasis sufferers try different solutions, always looking for the right product or combination to treat their symptoms. Identifying which treatment is most effective can be difficult. Talk to your doctor if you feel a treatment isn't working or you have uncomfortable side effects.
There are different types of psoriasis and the condition affects sufferers in various ways and grades of severity. Symptoms may range from barely noticeable to outbreaks that cover most of the body.
What triggers Psoriasis?
What causes psoriasis?
The predisposition for psoriasis is believed to be genetic, and there is no definitive cure. It can develop at any age.
While the exact causes remain unknown, research suggests it is caused by a problem with the immune system. There are indications that an auto-immune disorder is responsible, causing immune system T cells that usually attack bacteria or viruses, to mistakenly attack healthy skin cells. T cell activity also stimulates the overproduction of skin cells. A vicious cycle results, where the blood vessels are dilated, allowing more white blood cells than usual to enter the skin’s outer layer. This creates increased production of healthy cells, T cells and other white blood cells. In turn yet more white blood cells move to the outer layer, and so the cycle continues.
This underlying genetic condition combines with physical and environmental triggers to cause psoriasis.
It is the result of flare-ups that can be triggered by different substances and physical conditions, such as:
Injury to the skin
Any type of cut, graze, insect bite, infection or severe sunburn can trigger the condition. The so-called Koebner phenomenon also plays a role here, which is when new psoriasis outbreaks occur on what is referred to as “lines of trauma”. In other words, the condition can flare up at the site of any skin injury.
Excessive alcohol consumption
Excessive alcohol consumption can trigger a flare-up.
Excessive smoking consumption can trigger a flare-up.
Throat and respiratory infections
These infections coincide with psoriasis outbreaks of a particular type, known as guttate psoriasis. Psoriasis can be therefore be triggered by strep throat, colds and flu, bronchitis and so on.
It has been established that stress affects the immune system, causing it to react in the same way as to physical injury or infection. This contributes to the cycle of overproduction of skin cells.
These include lithium, some high blood pressure and heart medications (like beta blockers), and anti-malarial drugs. Speak to your Doctor or Pharmacist if you have any questions but don't stop taking any prescribed medication.
These are often the triggers for the first outbreak of psoriasis, particularly during puberty or menopause. It can have a somewhat unpredictable effect during pregnancy: symptoms can improve or disappear while a woman is pregnant, only to flare up after she has given birth.
- Injury to the skin
- Excessive alcohol consumption
- Throat and respiratory infections
- Certain medicines
- Hormonal changes
Who has Psoriasis?
Who has psoriasis?
Psoriasis affects 2 to 3 % of the total population1. Worldwide more than 120-million people suffer from this serious skin condition2. Men and women are equally affected. It can occur at any age, but is especially prevalent between the late teens and the 30s, and between the ages of 50 and 60. Perhaps the most significant risk factor is having a family history of psoriasis. If you have one parent with psoriasis it increases your risk of developing it yourself by around 30%. If both your parents have the condition, the risk rises to around 75%.
How to treat Psoriasis?
How to treat psoriasis?
There is still no cure for psoriasis, but by avoiding triggers and using an adequate treatment flare-ups can be managed. Depending on the severity of the affliction, different treatments and products are used to relieve the symptoms and help prevent future outbreaks.
First line treatment
Effective treatment of the symptoms begins with moisturizing the skin. As psoriasis is a dry skin condition, it’s important to keep the skin well moisturised with a special moisturizing cream or lotion.
Creams containing coal tar, a substance that helps to slow down the growth of skin cells can also be used. These products are known for their distinctive smell.
More advanced treatment
If these don’t treat the symptoms successfully, treatment can be stepped up to include prescription topical treatments, such as vitamin D creams, lotions, and ointments to slow down the skin growth. Topical steroids can also be used to fight the inflammation. Your doctor will help you develop the best treatment regime for you.
For severe cases
- UV light therapy (phototherapy)
- Oral or injected prescription medicines.
Dermalex Psoriasis Cream
This treatment is effective in relieving the symptoms, reducing cell growth and repairing the protective skin barrier. It is suitable for mild to moderate psoriasis and for long-term use .
In all cases, no matter what treatments are used, a healthy diet and good personal hygiene are also strongly advised.
Dermalex offers a cream and a gel for the treatment of mild to moderate psoriasis:
- Dermalex Psoriasis Cream for the treatment of body psoriasis
- Dermalex Scalp Psoriasis Gel for the treatment of scalp psoriasis (common in 50% off all psoriasis sufferers)
Dermalex treats the symptoms and helps prevent future outbreaks of psoriasis with a unique triple action:
- The unique MagneoliteTM complex  in Dermalex repairs the skin barrier and creates a protective layer on top of the skin to prevent moisture from escaping.
- Normalises the production rate of skin cells and reduces the scaling.
- Reduces irritation, itching and redness, and stimulates the skin’s own repair mechanism.
Dermalex Psoriasis and Dermalex Scalp Psoriasis contain no steroids and are suitable for long-term use [15, 17].
This product is a medical device.
Proven effective and well tolerated in clinical tests [15, 17]
By stimulating skin repair and regulating the growth of skin cells, Dermalex is clinically proven to improve the symptoms of psoriasis. In a clinical trial 80% of the patients saw an improvement of 50% or better in their psoriasis symptoms .
15. K, N., PASI-based clinical efficacy of Dermalex Psoriasis. 2006.
16. International, O.P., A unique trademarked complex, MagneoLite as the key ingredient of the product. 2015.
17. Fritz K, B.B., Scherer J, Open Label Clinical Study with Dermalex Psoriasis. 2008.
18. Levi-Schaffer, F., et al., Inhibition of proliferation of psoriatic and healthy fibroblasts in cell culture by selected Dead-sea salts. Pharmacology, 1996. 52(5): p. 321-8.
19. K, F., Open Label Study on Efficacy and Acceptance of Dermalex Scalp Psoriasis. 2011-2012.